| 1 | Huntsman LLC | $5.7B | -- | 75 |
| 2 | the h group bbt, inc | $58.4M | 350 | 60 |
| 3 | E. T. SIMONDS CONSTRUCTION COMPANY | $52.9M | 350 | 60 |
| 4 | VIC KOENIG CHEVROLET, INC | $51.0M | 125 | 60 |
| 5 | Li'l Skirts™ | $51.0M | 125 | 60 |
| 6 | VOGLER MOTOR, COMPANY INC. | $24.8M | 125 | 60 |
| 7 | Plaza Tire Service Inc | $23.8M | 125 | 60 |
| 8 | Th(i)NQ Ed | $21.3M | 125 | 60 |
| 9 | Koru Ltd. | $18.9M | 125 | 60 |
| 10 | Sopris Labs, LLC | $15.3M | 30 | 60 |
| 11 | santa fe trail school district | $14.3M | 125 | 60 |
| 12 | carbondale chsd 165 school district | $14.3M | 125 | 60 |
| 13 | SIU College of Business and Analytics | $14.3M | 125 | 60 |
| 14 | Marian Community Hospital | $12.6M | 125 | 60 |
| 15 | Basic Copper Inc | $12.2M | 30 | 60 |
| 16 | Peebles Department Stores | $12.2M | 30 | 60 |
| 17 | cristaudo’s cafe & bakery | $12.2M | 30 | 60 |
| 18 | personellized cakes & cafe | $12.2M | 30 | 60 |
| 19 | backcountry brownies | $12.2M | 30 | 60 |
| 20 | SD Solutions LLC | $11.8M | 125 | 60 |
| 21 | Mountain Closets | $7.1M | 30 | 50 |
| 22 | siu college of liberal arts | $7.0M | 750 | 50 |
| 23 | Red Hill Animal Center | $6.3M | 30 | 50 |
| 24 | Cherry Financial Services | $6.3M | 30 | 50 |
| 25 | Vogler Ford | $5.9M | 30 | 50 |
| 26 | Ike Honda Cars | $5.7M | 30 | 50 |
| 27 | action auto collision, llc | $5.7M | 30 | 50 |
| 28 | Quatro's Pizza | $5.1M | 125 | 50 |
| 29 | Murdale True Value Inc | $5.1M | 30 | 50 |
| 30 | coredination a movement studio | $5.0M | 30 | 50 |
| 31 | southern illinois ob gyn assoc sc | $5.0M | 30 | 50 |
| 32 | woodard wellness group llc | $5.0M | 30 | 50 |
| 33 | southern illinois foot & ankle clinic, limited | $5.0M | 30 | 50 |
| 34 | Stiles Office Solutions | $5.0M | 30 | 50 |
| 35 | Carbondale Nursing Home Inc | $4.9M | 30 | 50 |
| 36 | WDBX-Carbondale 91.1 FM Community Radio | $4.5M | 30 | 50 |
| 37 | a1 affordable chimney cleaning | $4.5M | 30 | 50 |
| 38 | m & m tile & woodworking | $4.5M | 30 | 50 |
| 39 | Regal Plumbing & Heating, Inc. | $4.5M | 30 | 50 |
| 40 | windriver development llc | $4.5M | 30 | 50 |
| 41 | harry carter contracting firm, llc | $4.5M | 30 | 50 |
| 42 | Schimpf Construction Inc | $4.5M | 30 | 50 |
| 43 | Innovative Painting Systems, Inc | $4.5M | 30 | 50 |
| 44 | C8 Excavation and Trucking, LLC | $4.5M | 30 | 50 |
| 45 | aspen digger, inc. | $4.5M | 30 | 50 |
| 46 | TeachTeam | $4.1M | 350 | 50 |
| 47 | o'guinn, jody allen | $4.1M | 30 | 50 |
| 48 | Leadership Development Program SIUC | $3.9M | 30 | 50 |
| 49 | arvesen water | $3.8M | 30 | 50 |
| 50 | SAE Saluki Baja | $3.7M | 30 | 50 |
| 51 | VocalLynx | $3.5M | 30 | 50 |
| 52 | Telephone Systems Consultants,Inc. | $3.5M | 30 | 50 |
| 53 | SIU International Student Council (ISC) | $3.4M | 30 | 50 |
| 54 | SIU School of Accountancy | $3.4M | 30 | 50 |
| 55 | SIU Career Development Center & Student Employment | $3.4M | 30 | 50 |
| 56 | trans american tech institute | $3.4M | 30 | 50 |
| 57 | Jackson County Ambulance Service | $3.0M | 30 | 50 |
| 58 | Summers Architectural Moldings | $3.0M | 5 | 50 |
| 59 | Illinois Small Business Development Center at SIU | $2.8M | 30 | 50 |
| 60 | Sure-Response | $2.8M | 30 | 50 |
| 61 | School of Information Systems and Applied Technologies | $2.8M | 30 | 50 |
| 62 | NewEDI | $2.8M | 30 | 50 |
| 63 | globeflower press | $2.8M | 30 | 50 |
| 64 | rocky mountains staffing | $2.6M | 30 | 50 |
| 65 | Trichilo Food Svc | $2.5M | 5 | 50 |
| 66 | The JAY Effect | $2.5M | 5 | 50 |
| 67 | Owen Brothers | $2.5M | 5 | 50 |
| 68 | executive divas cleaning llc | $2.3M | 125 | 50 |
| 69 | Beazer East | $2.2M | 30 | 50 |
| 70 | American Resources Group, Ltd. | $2.2M | 30 | 50 |
| 71 | Covenant Carpentry | $2.1M | 5 | 50 |
| 72 | Carbondale Cycle | $2.0M | 5 | 50 |
| 73 | Signs Around Town | $2.0M | 5 | 50 |
| 74 | Betsy Fisher, Inc | $2.0M | 5 | 50 |
| 75 | Murdale True Value | $2.0M | 5 | 50 |
| 76 | Ward Kia | $2.0M | 5 | 50 |
| 77 | Joseph W Scotchlas Funeral Hm | $2.0M | 5 | 50 |
| 78 | Roaring Fork Valley Co-Op | $2.0M | 5 | 50 |
| 79 | Roaring Fork Beer Company | $2.0M | 5 | 50 |
| 80 | Swell Spirits | $2.0M | 5 | 50 |
| 81 | jen's cafe, llc | $2.0M | 5 | 50 |
| 82 | Northeast Abstract Co Inc | $2.0M | 30 | 50 |
| 83 | alligator self-serve storage | $2.0M | 30 | 50 |
| 84 | airport commercial plaza & storage llc | $2.0M | 30 | 50 |
| 85 | apartment4u pine shores | $2.0M | 30 | 50 |
| 86 | crawford bonnie properties | $2.0M | 30 | 50 |
| 87 | JP’s Professional Window Cleaning | $1.9M | 30 | 50 |
| 88 | Medicare View, LLC | $1.8M | 5 | 50 |
| 89 | DAVE TAYLOR, INC. | $1.8M | 5 | 50 |
| 90 | AIRCADA | $1.8M | 5 | 50 |
| 91 | Adult Day Service | $1.6M | 30 | 50 |
| 92 | SIUC Student Ctr | $1.6M | 30 | 50 |
| 93 | M&B Engineered Solutions, Inc. | $1.6M | 5 | 50 |
| 94 | rf guys llc | $1.6M | 30 | 50 |
| 95 | cowboy & engines | $1.5M | 5 | 50 |
| 96 | SENATOR Paul Simon | $1.5M | 30 | 50 |
| 97 | Brandon Schmidt Goffinet | $1.5M | 30 | 50 |
| 98 | Feirich/Mager/Green/Ryan | $1.5M | 30 | 50 |
| 99 | SANTA FE TRAIL USD 434 | $1.5M | 125 | 50 |
| 100 | Brehm Preparatory School, Inc. | $1.5M | 125 | 50 |