| 1 | ADVANCED MICRO DEVICES INC | $34.6B | -- | 80 |
| 2 | sacred heart healthcare systems | $500.7M | 3,000 | 70 |
| 3 | Dispatch One LLC | $96.0M | 350 | 60 |
| 4 | muhlenberg college wescoe school of continuing education | $85.8M | 750 | 60 |
| 5 | Morris Black & Sons, Inc | $74.0M | 125 | 60 |
| 6 | Bennett Automotive Group | $69.4M | 350 | 60 |
| 7 | Continental Aftermarket North America | $66.6M | 350 | 60 |
| 8 | K. Heeps Inc. | $63.5M | 125 | 60 |
| 9 | Synaptic Consulting | $59.6M | 350 | 60 |
| 10 | Shangy's Craft Beer Wholesaler | $51.5M | 125 | 60 |
| 11 | JH BENNETT, INC | $51.0M | 125 | 60 |
| 12 | T.C. MOTOR CAR CO. DBA LEXUS OF LEHIGH VALLEY | $51.0M | 125 | 60 |
| 13 | Dacor Parts | $51.0M | 125 | 60 |
| 14 | United Freeway Transportation | $51.0M | 125 | 60 |
| 15 | venuenext | $50.9M | 750 | 60 |
| 16 | allentown brew works | $50.8M | 125 | 60 |
| 17 | JetPay now NCR Payment Solutions | $48.3M | 230 | 60 |
| 18 | Andesa | $45.9M | 125 | 60 |
| 19 | Safety National Casualty Corp | $45.9M | 125 | 60 |
| 20 | Sports Chalet Inc | $40.9M | 350 | 60 |
| 21 | O'Brien's Moving and Storage - Allied Van Lines | $34.3M | 125 | 60 |
| 22 | World Logistics USA Inc | $34.3M | 125 | 60 |
| 23 | ARMStaffing | $30.0M | 350 | 60 |
| 24 | General Mortgage Company | $26.3M | 125 | 60 |
| 25 | American Bank PA | $26.3M | 125 | 60 |
| 26 | Haldeman Lincoln | $24.8M | 125 | 60 |
| 27 | The Scott Family of Dealerships | $24.8M | 125 | 60 |
| 28 | Ciocca Subaru | $24.8M | 125 | 60 |
| 29 | toyo tire corp | $23.8M | 125 | 60 |
| 30 | Allentown Symphony Association | $23.2M | 125 | 60 |
| 31 | New Century Productions | $23.1M | 350 | 60 |
| 32 | Musselman Advertising Inc | $23.0M | 30 | 60 |
| 33 | Easy Signs USA | $22.9M | 125 | 60 |
| 34 | F.T. Silfies, Inc. | $22.5M | 125 | 60 |
| 35 | Aptean Equipment ERP | $21.3M | 125 | 60 |
| 36 | Aptean Food & Beverage ERP, JustFood Edition | $21.3M | 125 | 60 |
| 37 | american partners group | $21.0M | 350 | 60 |
| 38 | Haven House in Allentown PA | $20.9M | 125 | 60 |
| 39 | extended family care allentown | $20.9M | 125 | 60 |
| 40 | Hospital Central Services, Inc. & Affiliates | $20.9M | 125 | 60 |
| 41 | Spectrum Community Services Inc. | $20.9M | 125 | 60 |
| 42 | lehigh area medical associates,p.c. | $20.9M | 125 | 60 |
| 43 | orthopaedic associates of allentown | $20.9M | 125 | 60 |
| 44 | valley oral surgery pc | $20.9M | 125 | 60 |
| 45 | Historic Americus Hotel | $20.5M | 125 | 60 |
| 46 | Renaissance Allentown | $20.5M | 125 | 60 |
| 47 | Hyatt Place/Hyatt House Allentown/Lehigh Valley | $20.5M | 125 | 60 |
| 48 | JIM MELLON GENERAL CONTRACTING INC DBA MELLON CERTIFIED RESTORATION | $18.9M | 125 | 60 |
| 49 | Ace Electric Allentown,PA | $18.9M | 125 | 60 |
| 50 | The Butz Family of Companies | $18.9M | 125 | 60 |
| 51 | SolarTrak | $18.9M | 125 | 60 |
| 52 | Dual Temp Company | $18.9M | 125 | 60 |
| 53 | CSI Greater Lehigh Valley Chapter | $18.9M | 125 | 60 |
| 54 | Valley Doors and Hardware Inc | $18.9M | 125 | 60 |
| 55 | Ramset Redhead Inc | $18.9M | 125 | 60 |
| 56 | Lehigh County Medical Society of PA | $18.9M | 350 | 60 |
| 57 | QSC, Inc. (Quality Systems and Compliance) | $18.0M | 125 | 60 |
| 58 | Kilby Management | $17.8M | 30 | 60 |
| 59 | Ilkem Marble & Granite | $17.8M | 30 | 60 |
| 60 | Facade+Window Associates, LLC | $17.8M | 30 | 60 |
| 61 | Lehigh Valley Restaurant Brands | $16.6M | 131 | 60 |
| 62 | us power trade | $16.0M | 125 | 60 |
| 63 | Lehigh County Authority | $16.0M | 125 | 60 |
| 64 | Precise Design Group | $15.7M | 125 | 60 |
| 65 | ASHRAE Lehigh Valley Chapter | $15.3M | 125 | 60 |
| 66 | Bazzini Holdings | $15.3M | 30 | 60 |
| 67 | Diefenderfer Electrical/Telecommunications Contractors | $14.6M | 125 | 60 |
| 68 | Cenix Inc | $14.6M | 125 | 60 |
| 69 | pokémon club at muhlenberg college | $14.3M | 125 | 60 |
| 70 | PLS Classes | $14.3M | 125 | 60 |
| 71 | Lehigh Valley Safety Shoes a Division of Saf-Gard Safety Shoe Company | $12.6M | 125 | 60 |
| 72 | South Whitehall Township | $12.6M | 125 | 60 |
| 73 | Salisbury Township | $12.6M | 125 | 60 |
| 74 | Yorgey Supply Inc | $12.4M | 30 | 60 |
| 75 | kylie’s hair elements and supplies llc | $12.4M | 30 | 60 |
| 76 | Macmillan Oil of Allentown | $12.4M | 30 | 60 |
| 77 | Geiger Beverage | $12.4M | 30 | 60 |
| 78 | West Fruit Juice Co | $12.2M | 30 | 60 |
| 79 | Bennett Land Rover | $12.2M | 30 | 60 |
| 80 | Scott Chevrolet Cadillac | $12.2M | 30 | 60 |
| 81 | Handyman True Value | $12.2M | 30 | 60 |
| 82 | GymCrew | $12.2M | 30 | 60 |
| 83 | Chaar Saddlery Farm & Pet | $12.2M | 30 | 60 |
| 84 | Pressed Bouquet Shop | $12.2M | 30 | 60 |
| 85 | Friends Boutique | $12.2M | 30 | 60 |
| 86 | Soul Fashion | $12.2M | 30 | 60 |
| 87 | Dyeport | $12.2M | 30 | 60 |
| 88 | Fulfillment by 3LINX | $12.2M | 30 | 60 |
| 89 | TBL Services Inc. Division of BDP International | $12.2M | 30 | 60 |
| 90 | Dubir Dispatch | $12.2M | 30 | 60 |
| 91 | Pelicano | $12.2M | 30 | 60 |
| 92 | mr h2o | $12.2M | 30 | 60 |
| 93 | SPRUCEIT | $11.8M | 125 | 60 |
| 94 | RVS Solutions | $11.8M | 125 | 60 |
| 95 | Access Point Technology | $11.8M | 125 | 60 |
| 96 | Hl Yoh Co LLC | $11.8M | 125 | 60 |
| 97 | Plumlogix (MBE Salesforce Partner) | $11.8M | 125 | 60 |
| 98 | outten chevrolet of allentown | $11.6M | 125 | 60 |
| 99 | Vistacom Control Room Solutions | $11.1M | 125 | 60 |
| 100 | Forward Thinking Technology Solutions | $11.1M | 125 | 60 |