| 1 | Playtech
software industry | 708.6M | -- | 62 |
| 2 | The Isle of Man Steam Packet Company | 479.2M | 350 | 70 |
| 3 | International Contract Engineering Limited | 479.2M | 350 | 70 |
| 4 | ICE Marine Design Group | 479.2M | 350 | 70 |
| 5 | Isle of Man Department for Enterprise | 268.2M | 350 | 70 |
| 6 | Döhle (IOM) Ltd | 171.1M | 125 | 70 |
| 7 | Captive Insurance Isle of Man | 128.6M | 350 | 70 |
| 8 | Knox group of companies | 73.6M | 350 | 60 |
| 9 | Hansard | 73.6M | 350 | 60 |
| 10 | RL360 | 73.6M | 350 | 60 |
| 11 | Capital International Group | 73.6M | 350 | 60 |
| 12 | Isle of Man Transport | 62.9M | 350 | 60 |
| 13 | Sefton Group PLC | 57.5M | 350 | 60 |
| 14 | Robinson's Limited | 51.5M | 125 | 60 |
| 15 | Döhle Yachts | 41.1M | 30 | 60 |
| 16 | Riela Yachts | 41.1M | 30 | 60 |
| 17 | Isle of Man Ship Registry | 41.1M | 30 | 60 |
| 18 | Bernhard Schulte Shipmanagement Isle of Man | 41.1M | 30 | 60 |
| 19 | smartroam | 40.9M | 350 | 60 |
| 20 | Speed Networking Group | 38.4M | 350 | 60 |
| 21 | Ferber Enterprises | 36.2M | 125 | 60 |
| 22 | Skywind Group | 33.1M | 350 | 60 |
| 23 | CIPD Isle of Man Branch | 30.0M | 350 | 60 |
| 24 | Capital International | 27.3M | 130 | 60 |
| 25 | MANX FINANCIAL LIMITED | 26.3M | 125 | 60 |
| 26 | The ICM Group | 26.3M | 125 | 60 |
| 27 | IOMA Group | 26.3M | 125 | 60 |
| 28 | FXCDirect | 26.3M | 125 | 60 |
| 29 | Hobart Enterprises Limited | 26.3M | 125 | 60 |
| 30 | Nedbank Private Wealth International | 26.3M | 125 | 60 |
| 31 | Abacus Trust Group | 26.3M | 125 | 60 |
| 32 | Boston Multi Family Office | 26.3M | 125 | 60 |
| 33 | Beside Asset Management | 26.3M | 125 | 60 |
| 34 | Santander Work Café, Isle of Man | 26.3M | 125 | 60 |
| 35 | Isle of Man Financial Services Authority | 26.3M | 125 | 60 |
| 36 | Atla Group | 26.3M | 125 | 60 |
| 37 | MJ Fiduciary & Management Services | 26.3M | 125 | 60 |
| 38 | Anola Trading Limited | 26.3M | 125 | 60 |
| 39 | Canada Life International | 26.3M | 125 | 60 |
| 40 | GATG PLC | 23.8M | 125 | 60 |
| 41 | Inspiriom Benefit Corporation Ltd | 23.0M | 30 | 60 |
| 42 | GREEN CELL TECHNOLOGIES | 23.0M | 30 | 60 |
| 43 | Gateway Trade & Investments Ltd | 23.0M | 30 | 60 |
| 44 | LUX | 23.0M | 30 | 60 |
| 45 | MARTIN BURNS LIMITED | 21.9M | 125 | 60 |
| 46 | Prospero.Group | 21.8M | 350 | 60 |
| 47 | Platipus Ltd. | 16.1M | 125 | 60 |
| 48 | Yafibr | 14.6M | 125 | 60 |
| 49 | plan.com | 14.6M | 125 | 60 |
| 50 | WMX Global | 14.6M | 125 | 60 |
| 51 | Cycle 360 | 12.2M | 30 | 60 |
| 52 | Skanco Business Systems Limited | 11.8M | 125 | 60 |
| 53 | HubStars.Dating | 11.8M | 125 | 60 |
| 54 | Quanta | 11.8M | 125 | 60 |
| 55 | iBus Media | 11.1M | 125 | 60 |
| 56 | CTH Insurance | 11.0M | 30 | 60 |
| 57 | Kestrel Insurance | 11.0M | 30 | 60 |
| 58 | Constellation Engineering | 9.4M | 30 | 50 |
| 59 | Spot On Cleaners Limited | 9.3M | 125 | 50 |
| 60 | QA Travel Isle of Man | 8.5M | 30 | 50 |
| 61 | Island Business Travel | 8.5M | 30 | 50 |
| 62 | MannVend Ltd | 7.4M | 30 | 50 |
| 63 | CuppaCo.com | 7.4M | 30 | 50 |
| 64 | Isle of Man Meats | 7.4M | 30 | 50 |
| 65 | bath & bottle | 7.4M | 30 | 50 |
| 66 | Moore Dixon Isle of Man | 6.9M | 33 | 50 |
| 67 | Ellan Vannin Marine | 6.8M | 5 | 50 |
| 68 | Performar Ltd | 6.8M | 5 | 50 |
| 69 | Cornerstone Crew Management | 6.8M | 5 | 50 |
| 70 | Hospice Isle of Man | 6.7M | 125 | 50 |
| 71 | Knox House Trust Limited | 6.3M | 30 | 50 |
| 72 | CoinCorner | 6.3M | 30 | 50 |
| 73 | Turnstone Multi-Family Office | 6.3M | 30 | 50 |
| 74 | The Isle | 6.3M | 30 | 50 |
| 75 | Affinity Group | 6.3M | 30 | 50 |
| 76 | Acordias | 6.3M | 30 | 50 |
| 77 | SolutionsHub | 6.3M | 30 | 50 |
| 78 | Group Eleven | 6.3M | 30 | 50 |
| 79 | Oceanic Investment Management | 6.3M | 30 | 50 |
| 80 | The Law Trust Limited | 6.3M | 30 | 50 |
| 81 | Moni Talks | 6.3M | 30 | 50 |
| 82 | Financefolio | 6.3M | 30 | 50 |
| 83 | Galileo Fund Services Limited | 6.3M | 30 | 50 |
| 84 | Tokedo | 6.3M | 30 | 50 |
| 85 | DFK Chancery | 6.3M | 30 | 50 |
| 86 | Arzak Global Securities | 6.3M | 30 | 50 |
| 87 | Crowe Trust Isle of Man Limited | 6.3M | 30 | 50 |
| 88 | Manavia Limited | 6.3M | 30 | 50 |
| 89 | blackfridge | 6.3M | 30 | 50 |
| 90 | MJ PARTNERS & MANAGEMENTS SERVICE A subsidiary of Water Mayer Finance and Loans | 6.3M | 30 | 50 |
| 91 | Compare the Umbrella | 6.3M | 30 | 50 |
| 92 | 4esports | 6.3M | 30 | 50 |
| 93 | Chase Wealth Solutions | 6.3M | 30 | 50 |
| 94 | Döhle Corporate and Trust Services Limited | 6.3M | 30 | 50 |
| 95 | Counton Global Mobility Solutions | 6.3M | 30 | 50 |
| 96 | Edgewater | 6.3M | 30 | 50 |
| 97 | The Fortress Group | 6.3M | 30 | 50 |
| 98 | Cayman National Isle of Man | 6.3M | 30 | 50 |
| 99 | Mann Made Group | 6.3M | 30 | 50 |
| 100 | The Fedelta Group | 6.3M | 30 | 50 |