| 1 | university of crete international program in medicine | €343.3M | 3,000 | 70 |
| 2 | savoidakis s.a. | €142.3M | 350 | 70 |
| 3 | Stonetech | €74.0M | 125 | 60 |
| 4 | cretacargo transport l.p. | €71.8M | 750 | 60 |
| 5 | cretamel | €50.8M | 125 | 60 |
| 6 | kremel sa | €50.8M | 125 | 60 |
| 7 | University General Hospital of Heraklion "PAGNI" | €43.6M | 261 | 60 |
| 8 | Meeting Point Hellas | €35.5M | 125 | 60 |
| 9 | Foundation for Research and Technology - Hellas (FORTH) | €31.0M | 298 | 60 |
| 10 | zeus hotels papakaliatis bros s.a. | €30.5M | 750 | 60 |
| 11 | ICS-FORTH | €16.8M | 162 | 60 |
| 12 | Minoan Lines S.A. | €16.2M | 82 | 60 |
| 13 | knowledge transfer office - university of crete | €14.3M | 125 | 60 |
| 14 | vasia hotels & resorts | €14.2M | 350 | 60 |
| 15 | tba | €14.2M | 350 | 60 |
| 16 | golden hotels & resorts | €14.2M | 350 | 60 |
| 17 | omicron hotels | €14.2M | 350 | 60 |
| 18 | creta-oil botzakis s.a. | €12.2M | 30 | 60 |
| 19 | uniher s.a. | €12.2M | 30 | 60 |
| 20 | talianis s.a. | €12.2M | 30 | 60 |
| 21 | daskalakis manos s.a. | €12.2M | 30 | 60 |
| 22 | cretan mill s.a. | €12.2M | 30 | 60 |
| 23 | greek legend | €12.2M | 30 | 60 |
| 24 | botzakis s.a. | €12.2M | 30 | 60 |
| 25 | Smart Insole Project | €11.8M | 125 | 60 |
| 26 | Concept Techniki SA | €11.8M | 30 | 60 |
| 27 | Institute of Electronic Structure & Laser (IESL) - Foundation for Research and Technology - Hellas | €10.2M | 98 | 60 |
| 28 | Ideal sa | €7.8M | 125 | 50 |
| 29 | winco.windows.doors.facades | €7.8M | 30 | 50 |
| 30 | A Ilios | €6.8M | 30 | 50 |
| 31 | automatic premium solutions machines | €6.8M | 30 | 50 |
| 32 | Hamed SA | €6.5M | 16 | 50 |
| 33 | Proactive - Σύμβουλοι Επιχειρήσεων | €6.3M | 30 | 50 |
| 34 | kokolakis s.a. | €6.0M | 30 | 50 |
| 35 | karpos choraitis | €6.0M | 30 | 50 |
| 36 | konitsiotis s.a. | €6.0M | 30 | 50 |
| 37 | geo.per. consultants engineers s.a. | €5.9M | 30 | 50 |
| 38 | energycert.gr κατασκευαστική | €5.9M | 30 | 50 |
| 39 | proviop ltd | €5.7M | 30 | 50 |
| 40 | VR Lab GR | €5.1M | 30 | 50 |
| 41 | eurohotel s.a. | €5.1M | 125 | 50 |
| 42 | trend hotels greece | €5.1M | 125 | 50 |
| 43 | central hotel heraklion by ibis styles | €5.1M | 125 | 50 |
| 44 | hotel wellness spa services | €5.1M | 125 | 50 |
| 45 | castello hotels | €5.1M | 125 | 50 |
| 46 | castello hotels group | €5.1M | 125 | 50 |
| 47 | hellenic zeus | €5.1M | 125 | 50 |
| 48 | sentido unique blue resort | €5.1M | 125 | 50 |
| 49 | emmetropia s.a. mediterranean eye clinic | €5.0M | 30 | 50 |
| 50 | MK Hotel Collection | €4.9M | 30 | 50 |
| 51 | alikon chemicals ltd | €4.9M | 30 | 50 |
| 52 | temer ae | €4.5M | 30 | 50 |
| 53 | dolapsakis sa | €4.5M | 30 | 50 |
| 54 | livas sa | €4.5M | 30 | 50 |
| 55 | m manolidakis aeebe (2m) | €4.1M | 30 | 50 |
| 56 | food brokers | €3.8M | 5 | 50 |
| 57 | bountourakis | €3.8M | 30 | 50 |
| 58 | metalindustrial | €3.7M | 30 | 50 |
| 59 | Enartia | €3.5M | 27 | 50 |
| 60 | morfi educational group | €3.4M | 30 | 50 |
| 61 | FEA-VEE | €3.4M | 30 | 50 |
| 62 | Institute of Astrophysics, FORTH | €3.1M | 30 | 50 |
| 63 | cube concept - architectural design and building development office | €3.1M | 30 | 50 |
| 64 | ENISA Permanent Stakeholders Group | €3.0M | 30 | 50 |
| 65 | mortoglou.gr | €2.8M | 30 | 50 |
| 66 | ''mastelko'' - κολομβάκη αφροδίτη & σία ε.ε. | €2.8M | 30 | 50 |
| 67 | Entec Green Economy Consultants [GR] | €2.7M | 13 | 50 |
| 68 | dialynas s.a. environmental | €2.2M | 30 | 50 |
| 69 | creta eco phoenix | €2.2M | 30 | 50 |
| 70 | virtual trip ltd | €2.1M | 30 | 50 |
| 71 | mediterranean cloud booking services - mcbs | €2.1M | 30 | 50 |
| 72 | BanaNatural | €2.1M | 5 | 50 |
| 73 | myCretangoods | €2.0M | 5 | 50 |
| 74 | Malia Fancy Dress | €2.0M | 5 | 50 |
| 75 | Sbokos Destination Management Company I Crete | €2.0M | 30 | 50 |
| 76 | grelia | €2.0M | 5 | 50 |
| 77 | rem property management | €2.0M | 30 | 50 |
| 78 | Model General Lyceum of Heraklion | €1.8M | 16 | 50 |
| 79 | universal asset management investment services s.a. | €1.8M | 30 | 50 |
| 80 | Tourmie | €1.4M | 5 | 50 |
| 81 | otagate | €1.4M | 5 | 50 |
| 82 | tradeup catering supplies | €1.3M | 125 | 50 |
| 83 | Pasiphae Lab | €1.2M | 12 | 50 |
| 84 | Nut Nutter | €1.2M | 5 | 50 |
| 85 | fooda.gr | €1.2M | 5 | 50 |
| 86 | Quantum Biometronics | €1.2M | 5 | 50 |
| 87 | ocean heights view hotel (new oceanis s.a.) | €1.2M | 30 | 50 |
| 88 | webhoteldirect | €1.2M | 30 | 50 |
| 89 | chc group - chnaris hotel management, development & consulting | €1.2M | 30 | 50 |
| 90 | alsus crete escape - adults only | €1.2M | 30 | 50 |
| 91 | noima hospitality | €1.2M | 30 | 50 |
| 92 | anna maria village hotel | €1.2M | 30 | 50 |
| 93 | belvedere village agia pelagia creta | €1.2M | 30 | 50 |
| 94 | kosmos group | €1.2M | 30 | 50 |
| 95 | pagopoieion ice factory | €1.2M | 30 | 50 |
| 96 | foroepilisis s.a. | €1.1M | 30 | 50 |
| 97 | A2G Architects | €1.1M | 30 | 50 |
| 98 | phaistos networks s.a. | €1.0M | 125 | 50 |
| 99 | Inventive Energy KEM AE | €1.0M | 5 | 40 |
| 100 | ho.re.ca. foodplus s.a. | €995K | 5 | 40 |