| 1 | CREAPHARM BIO&PHARMA | €50.4M | 350 | 60 |
| 2 | IUT de Reims-Châlons-Charleville | €40.1M | 350 | 60 |
| 3 | chochoy consulting | €38.1M | 30 | 60 |
| 4 | astrazeneca reims | €34.2M | -- | -- |
| 5 | metanoia sante | €34.2M | -- | -- |
| 6 | s o d i a | €34.2M | -- | -- |
| 7 | ep finances sarl | €34.2M | -- | -- |
| 8 | laboratoires sodia sa | €34.2M | -- | -- |
| 9 | snc pharmacie bride | €34.2M | -- | -- |
| 10 | creapharm group | €34.2M | -- | -- |
| 11 | creapharm clinical supplies site de reims | €34.2M | -- | -- |
| 12 | Volkswagen Champagne - Intenz by autosphere | €24.8M | 125 | 60 |
| 13 | BMW MINI ENVERGURE Reims | €24.8M | 125 | 60 |
| 14 | Autosphere Fleet Champagne | €24.8M | 125 | 60 |
| 15 | MENG CONSULTING - SparklingPlus Asia | €23.0M | 30 | 60 |
| 16 | Alliance Partenaires Graphiques - Groupe Sprint | €22.9M | 125 | 60 |
| 17 | Halo Art | €15.9M | 125 | 60 |
| 18 | technic assistance groupe | €15.3M | 125 | 60 |
| 19 | Inspé de l'académie de Reims (au sein de l'URCA) | €14.3M | 125 | 60 |
| 20 | IRTS de Champagne-Ardenne | €14.3M | 125 | 60 |
| 21 | guerriero sophie | €13.8M | -- | 60 |
| 22 | tim sa france | €12.4M | 30 | 60 |
| 23 | Ets Alain Compas | €12.4M | 30 | 60 |
| 24 | mgrtp | €11.8M | 30 | 60 |
| 25 | Flat6 Assurances | €11.0M | 30 | 60 |
| 26 | jelly week 🐙 | €10.6M | 30 | 60 |
| 27 | aef production reims | €10.5M | -- | -- |
| 28 | pfleiderer france | duropal - thermopal | €10.5M | -- | -- |
| 29 | scm bois | €10.5M | -- | -- |
| 30 | innov'orga | €9.4M | -- | -- |
| 31 | maestria beaute | €9.4M | -- | -- |
| 32 | kem one innovative vinyls sas | €9.4M | -- | -- |
| 33 | parchimy | €9.4M | -- | -- |
| 34 | blossom clinic - dépilab by blossom | €9.4M | -- | -- |
| 35 | NOAH ReGen | €9.3M | 125 | 50 |
| 36 | Keller Williams Grand Cru | €8.2M | 125 | 50 |
| 37 | bts bâtiment arago reims | €7.3M | -- | -- |
| 38 | desgrippes père et fils | €7.3M | -- | -- |
| 39 | sarl espal | €7.3M | -- | -- |
| 40 | maconnerie generale - berat | €7.3M | -- | -- |
| 41 | société d'installation de rénovation d'equipement du bâtiment | €7.3M | -- | -- |
| 42 | nola travaux spéciaux | €7.3M | -- | -- |
| 43 | HOPTEAM HAUTS DE FRANCE | €7.2M | 30 | 50 |
| 44 | aéroclub du crna/est | €6.7M | -- | -- |
| 45 | reims aviation industrie | €6.7M | -- | -- |
| 46 | MELIAË | €6.6M | 30 | 50 |
| 47 | sarl edpro | €6.4M | -- | -- |
| 48 | coffr'alarm | €6.4M | -- | -- |
| 49 | guerineau reims s.a. | €6.4M | -- | -- |
| 50 | cevolta | €6.4M | -- | -- |
| 51 | ip netcom | €6.4M | -- | -- |
| 52 | seyfert packaging s.a.s. | €6.1M | -- | -- |
| 53 | vintacap france sarl | €6.1M | -- | -- |
| 54 | palm packaging france | €6.1M | -- | -- |
| 55 | s.a.r.l. avenir pvc | €6.1M | -- | -- |
| 56 | ateliers roche - le sur-mesure industriel | €6.0M | -- | -- |
| 57 | adv packaging champagne | €6.0M | -- | -- |
| 58 | novae aerospace industry | €6.0M | -- | -- |
| 59 | societe industrielle d'interventions | €6.0M | -- | -- |
| 60 | inventustry s.a.s. | €6.0M | -- | -- |
| 61 | serm société d'etudes et de réalisations mécaniques | €6.0M | -- | -- |
| 62 | ecobulles® | €6.0M | -- | -- |
| 63 | csautomatisme | €6.0M | -- | -- |
| 64 | actemium reims | €6.0M | -- | -- |
| 65 | rpsi maintenance industrielle | €6.0M | -- | -- |
| 66 | altéad industries est | €6.0M | -- | -- |
| 67 | mri industries | €6.0M | -- | -- |
| 68 | piper heidsieck c.c. | €6.0M | 30 | 50 |
| 69 | Toyota - T.T.R automobiles | €5.9M | 30 | 50 |
| 70 | Audi Reims - Quantium by autosphere | €5.9M | 30 | 50 |
| 71 | Nissan Est - Nyxo Reims by Autosphere | €5.9M | 30 | 50 |
| 72 | Festival Nuits Sans Entractes | €5.6M | 30 | 50 |
| 73 | Liste BDA Supernov'art | €5.6M | 30 | 50 |
| 74 | 843 patrimoine | €5.2M | -- | -- |
| 75 | uni santé prévoyance | €5.2M | -- | -- |
| 76 | assurance maladie marne (cpam) | €5.2M | -- | -- |
| 77 | abeille assurances - sarl pelletier dervin | €5.2M | -- | -- |
| 78 | axa brion dumoulin | €5.2M | -- | -- |
| 79 | assurances regnier chaudre | €5.2M | -- | -- |
| 80 | groupama nord-est | €5.2M | -- | -- |
| 81 | espace assurances - l'entente assurances | €5.2M | -- | -- |
| 82 | abeille assurances - afer - reims | €5.2M | -- | -- |
| 83 | Assurance Maladie Marne | €5.2M | -- | -- |
| 84 | courtierencrédits | €5.2M | -- | -- |
| 85 | bci assurances | €5.2M | -- | -- |
| 86 | ospro assurances | €5.2M | -- | -- |
| 87 | assurances reims cathedrale | €5.2M | -- | -- |
| 88 | walbaum latinamerica | €5.2M | -- | -- |
| 89 | transconseil assurances | €5.2M | -- | -- |
| 90 | nomophone | €5.1M | -- | -- |
| 91 | continental reims | €4.9M | 30 | 50 |
| 92 | BTS CG REIMS | €4.6M | 125 | 50 |
| 93 | Derinbat construction | €4.5M | 30 | 50 |
| 94 | sarl leova | €4.5M | 30 | 50 |
| 95 | Crèche Clairmarais | €4.0M | -- | -- |
| 96 | Master de géopolitique de Reims | €3.4M | 30 | 50 |
| 97 | EFRA ⏩Ecole Française de l'Alternance - 📍REIMS | €3.4M | 30 | 50 |
| 98 | Groupe Saint-Michel Reims | €3.4M | 30 | 50 |
| 99 | Master EA | Chargé d'études en Environnement, Développement Durable et Transition Ecologique | €3.4M | 30 | 50 |
| 100 | reactif service plus | €3.4M | -- | -- |