| 1 | apojee | €570.5M | 3,000 | 70 |
| 2 | fondation université d'auvergne (fuda) | €186.6M | 20,000 | 70 |
| 3 | michelin solutions | €52.9M | 750 | 60 |
| 4 | delaire sa | €38.1M | 30 | 60 |
| 5 | snc pharmacie lavoisier | €34.2M | -- | -- |
| 6 | laboratoires d'etudes et de recherches en oligo elements therapie | €34.2M | -- | -- |
| 7 | pharmacie claris dorut | €34.2M | -- | -- |
| 8 | pharmacie dorut | €34.2M | -- | -- |
| 9 | théa pharma france | €34.2M | -- | -- |
| 10 | association des étudiants en pharmacie option industrie de clermont-ferrand | €34.2M | -- | -- |
| 11 | cryoport systems (formerly cell&co) | €34.2M | -- | -- |
| 12 | aptys pharma | €34.2M | -- | -- |
| 13 | probionov | €34.2M | -- | -- |
| 14 | théacademy | €34.2M | -- | -- |
| 15 | laboratoires kôl | €34.2M | -- | -- |
| 16 | pharmacie viviani snc | €34.2M | -- | -- |
| 17 | CARTEN AUVERGNE CITROEN CLERMONT-FD ISSOIRE | €23.8M | 125 | 60 |
| 18 | fuji electric france s.a.s. | €22.5M | 125 | 60 |
| 19 | RMT Actia PROT&IN | €15.3M | 30 | 60 |
| 20 | ESC Clermont Business School | €14.3M | 125 | 60 |
| 21 | Alumni CPGE Fénelon Auvergne | €14.3M | 125 | 60 |
| 22 | Ecole d'Economie - CERDI | €14.3M | 125 | 60 |
| 23 | IAE Clermont Auvergne - School of Management | €14.3M | 125 | 60 |
| 24 | girard auriane | €13.8M | -- | 60 |
| 25 | simply market - côte blatin | €13.8M | -- | 60 |
| 26 | aguad nassima nedjma | €13.8M | -- | 60 |
| 27 | medic centre industrie - epi | €12.4M | 30 | 60 |
| 28 | Mazda Clermont-Ferrand Automobiles RVO | €12.2M | 30 | 60 |
| 29 | akelis agencement | €10.5M | -- | -- |
| 30 | ecobois 63 | €10.5M | -- | -- |
| 31 | nos forêts d'auvergne | €10.5M | -- | -- |
| 32 | selarl pharmacie ducher | €9.4M | 30 | 50 |
| 33 | pierre guillaume paris | €9.4M | -- | -- |
| 34 | noreva groupe | €9.4M | -- | -- |
| 35 | body'minute clermont-ferrand | €9.4M | -- | -- |
| 36 | laboratoires syha | €9.4M | -- | -- |
| 37 | funel | €9.4M | -- | -- |
| 38 | dorthz s.a.s. | €9.4M | -- | -- |
| 39 | laboratoire altheys | €9.4M | -- | -- |
| 40 | dorthz - compagnie france chimie ii | €9.4M | -- | -- |
| 41 | philippe bérangé flagrance | €9.4M | -- | -- |
| 42 | stayla france | €9.4M | -- | -- |
| 43 | païma beauté | €9.4M | -- | -- |
| 44 | automobiles r v o | €9.2M | 30 | 50 |
| 45 | SAS EURO DORTHZ PRODUCTION | €8.7M | 30 | 50 |
| 46 | ANEF 63 | €8.6M | 350 | 50 |
| 47 | sogeco batiment | €7.3M | -- | -- |
| 48 | societe d'equipement de l'auvergne | €7.3M | -- | -- |
| 49 | bati-dômes | €7.3M | -- | -- |
| 50 | deco+63 | €7.3M | -- | -- |
| 51 | btp courtadon entreprise | €7.3M | -- | -- |
| 52 | hairstore.fr | €7.2M | 30 | 50 |
| 53 | Dense Fluid Degreasing | €7.0M | 30 | 50 |
| 54 | MC2 Rénovation Énergétique | €6.8M | 30 | 50 |
| 55 | sunaero mro & services | €6.7M | -- | -- |
| 56 | atelier industriel de l'aéronautique de clermont-fd | €6.7M | -- | -- |
| 57 | saem transports en commun agglo clermo | €6.7M | -- | -- |
| 58 | aviation structure assistance- sunaero cfe | €6.7M | -- | -- |
| 59 | logistiques nicolas, sas | €6.7M | -- | -- |
| 60 | kubia innovative solutions | €6.4M | -- | -- |
| 61 | jcelec - hydro store | €6.4M | -- | -- |
| 62 | anthony sassano technicien electrique | €6.4M | -- | -- |
| 63 | emc2 - 63 | €6.4M | -- | -- |
| 64 | lg energy | €6.4M | -- | -- |
| 65 | santerne auvergne | €6.4M | -- | -- |
| 66 | sarl alain papon | €6.4M | -- | -- |
| 67 | eole- energies | €6.4M | -- | -- |
| 68 | concept & technologie | €6.4M | -- | -- |
| 69 | edabi | €6.4M | -- | -- |
| 70 | le tableau monte et cable - tmc | €6.4M | -- | -- |
| 71 | finanzierung kredit | €6.3M | 30 | 50 |
| 72 | cartonnages thomas - clermont ferrand | €6.1M | -- | -- |
| 73 | a2m auvergne maintenance & motorisations | €6.0M | -- | -- |
| 74 | mydis (hvs group) | €6.0M | -- | -- |
| 75 | auvergne techniques de pointe | €6.0M | -- | -- |
| 76 | montferrand mecanique | €6.0M | -- | -- |
| 77 | m.a.m. mesure asservissement machines - distributeur heidenhain | €6.0M | -- | -- |
| 78 | vibropercussion | €6.0M | -- | -- |
| 79 | r.j. sorema | €6.0M | -- | -- |
| 80 | erpi, etudes et réalisations de produits industriels | €6.0M | -- | -- |
| 81 | polynov - l'ingénierie sur mesure | €6.0M | -- | -- |
| 82 | atelier de tolerie et mecanique du centre | €6.0M | -- | -- |
| 83 | delta 2i | €6.0M | -- | -- |
| 84 | qarboon (ex-dense fluid degreasing) | €6.0M | -- | -- |
| 85 | cmf shanghai | €6.0M | -- | -- |
| 86 | axibois | €6.0M | -- | -- |
| 87 | trelleborg industrial hoses | €6.0M | -- | -- |
| 88 | trelleborg oil & marine | €6.0M | -- | -- |
| 89 | dfd sa /dense fluid degreasing | €6.0M | -- | -- |
| 90 | Opel Clermont-Ferrand | €5.9M | 30 | 50 |
| 91 | Centre Hyundai Entreprises Clermont Ferrand - AUTO16 | €5.7M | 30 | 50 |
| 92 | c v s assurances | €5.2M | -- | -- |
| 93 | clermont lafayette | €5.2M | -- | -- |
| 94 | expertises solutions | €5.2M | -- | -- |
| 95 | les z'experts | €5.2M | -- | -- |
| 96 | crédit agricole centre france - gaillard | €5.2M | -- | -- |
| 97 | gan assurances clermont centre | €5.2M | -- | -- |
| 98 | cvs & associes | €5.2M | -- | -- |
| 99 | mutuelle du chu — puy-de-dôme | €5.2M | -- | -- |
| 100 | christophe archer et michel chaizy agents generaux associes | €5.2M | -- | -- |