| 1 | Alimerka | €830.0M | 6,863 | 56 |
| 2 | Genei.es | €51.0M | 125 | 60 |
| 3 | Instituto de Investigación Sanitaria del Principado de Asturias | €36.4M | 350 | 60 |
| 4 | García Rodríguez Hermanos S.A. | €29.2M | 125 | 60 |
| 5 | dsd tecnología | €28.2M | 125 | 60 |
| 6 | EXIOM FOOD S.L | €24.9M | 125 | 60 |
| 7 | brondo | €23.0M | 30 | 60 |
| 8 | Las Caldas Villa Termal by blau hotels | €20.5M | 125 | 60 |
| 9 | AFEIRA ASTURIAS, S.L. | €20.5M | 125 | 60 |
| 10 | Colegio San Ignacio de Oviedo | €19.2M | 350 | 60 |
| 11 | EQUIPAMIENTOS HOSTELEROS Y LIMPIEZA INDUSTRIAL SL | €17.8M | 30 | 60 |
| 12 | Facultad Padre Ossó | €14.3M | 125 | 60 |
| 13 | Escuela de Ingenieria de Minas, Energía y Materiales de Oviedo (EIMEM) | €14.3M | 125 | 60 |
| 14 | instituto universitario fernández-vega | €14.3M | 125 | 60 |
| 15 | IUDE-Escuela de Negocios. Universidad de Oviedo | €14.3M | 125 | 60 |
| 16 | BRUSH PDO DE ASTURIAS SL | €12.4M | 30 | 60 |
| 17 | NOVAL & ZAMAK SL | €12.2M | 30 | 60 |
| 18 | ESPAÑOLA DE CONFECCION TEXTIL LA GRISETA SL | €12.2M | 30 | 60 |
| 19 | video cambio 100 sl | €12.2M | 30 | 60 |
| 20 | AUTOVIELLA SL | €12.2M | 30 | 60 |
| 21 | INTEY INTERIORES SL | €12.2M | 30 | 60 |
| 22 | AQF IMAGEN DIGITAL SL | €12.2M | 30 | 60 |
| 23 | D4 INTERIORISMO SL | €12.2M | 30 | 60 |
| 24 | IBERSA DE PINTURAS CUBANAS SL | €8.7M | 30 | 50 |
| 25 | Transportes Galastur, S.L | €8.2M | 30 | 50 |
| 26 | PIDAC Arquitectura e Ingeniería SL | €8.2M | 125 | 50 |
| 27 | inversiones petroliferas las palmeras sa | €8.1M | 5 | 50 |
| 28 | INIXA DEL PRINCIPADO SL | €8.0M | 30 | 50 |
| 29 | FIBRA OPTICA 3000 SL | €8.0M | 30 | 50 |
| 30 | COSMOARQUITECTURA SL | €8.0M | 30 | 50 |
| 31 | NUEVAS ENERGIAS ANDINAS SA | €8.0M | 30 | 50 |
| 32 | LOGISTICA Y TRANSPORTES DE ASTURIAS 2003 SL | €7.3M | 30 | 50 |
| 33 | OPTICAL DAION SL | €7.0M | 30 | 50 |
| 34 | Seaphase Underwater Services S.L. | €6.8M | 5 | 50 |
| 35 | PROGRESO FORESTAL SL | €6.3M | 30 | 50 |
| 36 | CONSTRUCCIONES Y REFORMAS PUERTO BOLIVAR SL | €6.0M | 30 | 50 |
| 37 | asociación círculo empresas | €5.5M | 30 | 50 |
| 38 | IMPRESION DIGITAL RIGEL SL | €5.5M | 30 | 50 |
| 39 | Ingeca: Ingeniería y Calidad Sostenible | €5.2M | 30 | 50 |
| 40 | Virtway | Events & Training Metaverse | €5.1M | 30 | 50 |
| 41 | TURISMO ASTURIAS PROMOCION Y GESTION SL | €4.9M | 30 | 50 |
| 42 | CAFE ISLA DE CUBA SL | €4.9M | 30 | 50 |
| 43 | hotel carbayon sl | €4.9M | 30 | 50 |
| 44 | EL PIGÜEÑA RESTAURANTE | €4.9M | 30 | 50 |
| 45 | INSTALACIONES ELECTRICAS GUERRA SL | €4.5M | 30 | 50 |
| 46 | Quantum FIX | €4.5M | 30 | 50 |
| 47 | Sardalla española | €4.5M | 30 | 50 |
| 48 | rehabilitación integral asturiana “riastur.es"" | €4.5M | 30 | 50 |
| 49 | cero computer sl | €3.9M | 30 | 50 |
| 50 | previnco sll | €3.9M | 30 | 50 |
| 51 | OLILU GENERACION SOLAR SL | €3.8M | 30 | 50 |
| 52 | Exportar Online | €3.8M | 5 | 50 |
| 53 | HASF | €3.8M | 5 | 50 |
| 54 | siapro eventos sl | €3.3M | 30 | 50 |
| 55 | impulsAsturias | €3.1M | 125 | 50 |
| 56 | Real Cuerpo de la Nobleza del Principado de Asturias | €3.1M | 125 | 50 |
| 57 | Consejería de Ciencia, Empresas, Formación y Empleo del Principado | €3.0M | 30 | 50 |
| 58 | FERROVIEDO SL | €3.0M | 5 | 50 |
| 59 | Doc-it, Gestión de Documentos | €2.7M | 30 | 50 |
| 60 | GRUPO IMPULTEC SL | €2.7M | 30 | 50 |
| 61 | INTEGRA PYME | €2.6M | 30 | 50 |
| 62 | Filosofía Kosher | €2.5M | 5 | 50 |
| 63 | agavus | €2.3M | 5 | 50 |
| 64 | grupo natura | €2.0M | 5 | 50 |
| 65 | ORTOPEDIA TECNICA VICARIO SL | €2.0M | 5 | 50 |
| 66 | MOVEO - Muestra de la Movilidad Sostenible de Oviedo | €2.0M | 5 | 50 |
| 67 | confeda sl | €2.0M | 30 | 50 |
| 68 | CONSTRUCTORA NARANJO DE BULNES SL | €2.0M | 30 | 50 |
| 69 | estudio principado | empresa constructora | €2.0M | 5 | 50 |
| 70 | ipreco 2014 sl | €2.0M | 5 | 50 |
| 71 | instalacion y climatizacion zeno astur sl | €2.0M | 5 | 50 |
| 72 | CYMTRA ASTURIAS AGENCIA DE SEGUROS SL | €1.8M | 5 | 50 |
| 73 | juan ramon nieto llera | €1.8M | 5 | 50 |
| 74 | Seguros Caser Trubia | €1.8M | 5 | 50 |
| 75 | carcaba sl | €1.8M | 30 | 50 |
| 76 | control de gestion y soluciones legales sl | €1.8M | 5 | 50 |
| 77 | clinica veterinaria quiros sl | €1.7M | 5 | 50 |
| 78 | Machín Cavallé - Salud y Estética Dental | €1.6M | 30 | 50 |
| 79 | wanacars | €1.5M | 5 | 50 |
| 80 | humboldt & elcano | €1.4M | 5 | 50 |
| 81 | SOCIEDAD MINERA EL TERRIBLE SL | €1.3M | 5 | 50 |
| 82 | PROCINSA INGENIERIA SA | €1.3M | 5 | 50 |
| 83 | ASTUR NUTS, S.L | €1.2M | 5 | 50 |
| 84 | JEFFREY'S BAY SKATE SL | €1.2M | 30 | 50 |
| 85 | VILLARAMA SL | €1.2M | 30 | 50 |
| 86 | pizzeria la competencia oviedo i sl | €1.2M | 30 | 50 |
| 87 | Toldos TOLDOSAN | €1.2M | 5 | 50 |
| 88 | VELO ENERGY | €1.1M | 5 | 50 |
| 89 | sgg aguas | €1.1M | 5 | 50 |
| 90 | jl refrigeracion | €1.1M | 5 | 50 |
| 91 | ANGEL CARREÑO ASESORIA MERCANTIL SL | €1.1M | 30 | 50 |
| 92 | gespasa consultores | €1.1M | 30 | 50 |
| 93 | FARMACOR 5P SL | €1.1M | 5 | 50 |
| 94 | OFICINA RACIONAL Y TECNICA SL | €1.1M | 30 | 50 |
| 95 | DPG Family Office | €1.1M | 5 | 50 |
| 96 | COFIPER CONSULTORES SL | €1.1M | 5 | 50 |
| 97 | LMQ Consulting & Advisory | €1.1M | 5 | 50 |
| 98 | ingenieria y geologia consultores s.l. | €1.0M | 5 | 50 |
| 99 | RO.PA. FASHION GROUP SL | €1.0M | -- | 62 |
| 100 | FORASTUR SA | €1.0M | 29 | 62 |