| 1 | E.ON SE | €60.9B | 87,067 | 69 |
| 2 | thyssenkrupp AG | €35.0B | 99,981 | 69 |
| 3 | HOCHTIEF Aktiengesellschaft | €27.8B | 36,858 | 69 |
| 4 | RWE Aktiengesellschaft | €24.5B | 18,246 | 69 |
| 5 | Aldi Nord
retail | €24.2B | 88,000 | 67 |
| 6 | ALDI Nord International Holding GmbH | €22.8B | 73,934 | 69 |
| 7 | BRENNTAG SE | €19.4B | -- | 69 |
| 8 | Evonik Industries AG | €12.2B | 31,053 | 69 |
| 9 | Lenovo Computer AG | €1.3B | 1,007 | 69 |
| 10 | FUNKE MEDIENGRUPPE GmbH & Co. KGaA | €1.1B | 6 | 69 |
| 11 | ifm electronic gmbh | €1.0B | 68 | 69 |
| 12 | Open Grid Europe GmbH | €925.6M | 1,486 | 69 |
| 13 | Contilia GmbH | €545.1M | 5,975 | 69 |
| 14 | Aldi Einkauf SE & Co. oHG | €479.4M | 1,974 | 69 |
| 15 | RAG-Stiftung | €461.3M | 21 | 69 |
| 16 | Universität Duisburg-Essen | €302.4M | 506 | 70 |
| 17 | Mr. Wash Autoservice AG | €260.2M | 2,021 | 69 |
| 18 | ferrostaal automotive | €142.6M | 750 | 70 |
| 19 | DIAG - Deutsche Industrieanlagen GmbH | €95.8M | 125 | 60 |
| 20 | Entwässerung Essen GmbH (EEG) | €82.7M | 6 | 69 |
| 21 | VMZINC Deutschland | €74.0M | 125 | 60 |
| 22 | RAG Montan Immobilien GmbH | €73.6M | 151 | 69 |
| 23 | diwi germany | €69.3M | 350 | 60 |
| 24 | frigoblock gmbh | €62.9M | 350 | 60 |
| 25 | connect2 services gmbh | €54.5M | 3,000 | 60 |
| 26 | Beyond Conventions | €45.0M | 125 | 60 |
| 27 | atp magazin - Automatisierung und digitale Transformation | €45.0M | 125 | 60 |
| 28 | e.on country hub germany gmbh (human resources) | €44.9M | 350 | 60 |
| 29 | Bischöfliche Aktion Adveniat e.V. | €43.1M | 87 | 69 |
| 30 | Maass Global Group - Wilhelm Maass GmbH | €39.2M | 125 | 60 |
| 31 | kliniken-essen-mitte | €37.7M | 3,000 | 60 |
| 32 | Der Wassermeister - News für echte Meister der Wasserwirtschaft | €35.3M | 125 | 60 |
| 33 | timeframe AG | €33.1M | 350 | 60 |
| 34 | Portawin Kriege GmbH | €32.4M | 125 | 60 |
| 35 | myneva Group GmbH | €31.1M | 350 | 60 |
| 36 | Schwarzer Precision GmbH | €29.2M | 125 | 60 |
| 37 | eku.sim | €28.2M | 125 | 60 |
| 38 | Industrial Valves | €25.0M | 125 | 60 |
| 39 | HOCHTIEF ViCon | €24.8M | 125 | 60 |
| 40 | BELEUCHTEN.EU | €23.7M | 125 | 60 |
| 41 | immobilien management essen gmbh (ime) | €22.9M | 350 | 60 |
| 42 | Diakoniewerk Essen Kindertagesbetreuung gGmbH | €21.0M | -- | 69 |
| 43 | fusion5 performance group gmbh | €20.9M | 125 | 60 |
| 44 | ORDNERSCHMIEDE | €20.7M | 125 | 60 |
| 45 | dahlem beratende ingenieure | €18.9M | 125 | 60 |
| 46 | DRS Group GmbH | €17.2M | 528 | 69 |
| 47 | 3R - Magazin für den Rohrleitungsbau | €16.0M | 125 | 60 |
| 48 | Deutsche Giga Access GmbH | €14.6M | 125 | 60 |
| 49 | Medizinisches Versorgungszentrum für Labormedizin und Mikrobiologie Ruhr GmbH | €14.4M | 151 | 69 |
| 50 | myneva Deutschland GmbH | €14.2M | 4 | 69 |
| 51 | e.bootis ag | €12.7M | 5 | 69 |
| 52 | CEYLAN Online | €12.4M | 30 | 60 |
| 53 | Zoomyo Health | €12.4M | 30 | 60 |
| 54 | Wohnungsgenossenschaft Essen-Nord eG | €12.2M | 17 | 69 |
| 55 | ASW Consulting GmbH | €12.2M | 30 | 60 |
| 56 | Hessefort GmbH | €12.2M | 30 | 60 |
| 57 | EKu.LOC | €11.8M | 125 | 60 |
| 58 | ebootis ag | €11.8M | 125 | 60 |
| 59 | AMANA - a LucaNet company | €11.8M | 125 | 60 |
| 60 | AMANA Tax | €11.8M | 125 | 60 |
| 61 | zipcon consulting | €10.6M | 30 | 60 |
| 62 | vitronet Holding GmbH | €10.3M | -- | 69 |
| 63 | gwf Wasser+Abwasser - Magazin | €9.3M | 125 | 50 |
| 64 | elite consulting | €8.8M | 125 | 50 |
| 65 | promwad, electronics design house | €8.8M | 125 | 50 |
| 66 | amana consulting | €8.8M | 125 | 50 |
| 67 | ARSATEC GmbH | €8.3M | 30 | 69 |
| 68 | Argus Productions DE | €8.3M | 125 | 50 |
| 69 | DHF Fulfillment Management GmbH | €8.2M | 30 | 50 |
| 70 | Allbau Managementgesellschaft mbH | €8.2M | 125 | 50 |
| 71 | poetree homes llp | €8.2M | 125 | 50 |
| 72 | Dipl.-Ing. Scherzer GmbH | €7.7M | -- | 69 |
| 73 | CONDOR Schutz- und Sicherheitsdienst GmbH | €7.6M | 143 | 69 |
| 74 | von buddenbrock gruppe | €7.5M | 125 | 50 |
| 75 | LURGI BISCHOFF GMBH | €7.0M | 30 | 50 |
| 76 | H2 NEWS | €6.8M | 30 | 50 |
| 77 | Zenit-SIS GmbH - powered by E.ON | €6.8M | 30 | 50 |
| 78 | Themys & Dyke Rechtsanwälte GbR | €6.3M | 125 | 50 |
| 79 | Kümmerlein Rechtsanwälte & Notare | €6.3M | 125 | 50 |
| 80 | KMAG Krusche Mohr Ahrens Gögel PartG mbB | €6.3M | 30 | 50 |
| 81 | DÜCKER & PARTNER | €6.3M | 30 | 50 |
| 82 | Ursula Dreyer | €6.3M | 30 | 50 |
| 83 | Studentischer Börsenclub Essen | €6.3M | 30 | 50 |
| 84 | Bitcoin2Go | €6.3M | 30 | 50 |
| 85 | theater und philharmonie essen | €6.0M | 750 | 50 |
| 86 | asdro gmbh | €6.0M | 30 | 50 |
| 87 | F&S International - Filtration and Separation | €6.0M | 30 | 50 |
| 88 | wecon netzwerk essen | €5.5M | 30 | 50 |
| 89 | Bankhaus Bauer Aktiengesellschaft | €5.5M | 22 | 69 |
| 90 | Gradoo Publish | €5.5M | 30 | 50 |
| 91 | opta data Stiftung & Co. KG | €5.2M | 200 | 69 |
| 92 | Time 365 | €5.1M | 30 | 50 |
| 93 | Metall Kanban | €5.1M | 30 | 50 |
| 94 | green club 💚 | €5.1M | 125 | 50 |
| 95 | RLT Ruhrmann Tieben & Partner mbB | €4.6M | 125 | 50 |
| 96 | Techno-Physik Engineering GmbH | €4.5M | 2,021 | 69 |
| 97 | Ruhrverband | €4.5M | 70 | 69 |
| 98 | Ruhr-Objekt-4 GmbH | €4.4M | -- | 69 |
| 99 | Bildungsinstitut Ruhrschule | €4.1M | 125 | 50 |
| 100 | CarboTech AC GmbH | €4.0M | -- | 69 |